Magnetic Resonance Imaging: Basic Principles

                                             Orhan  Konez, MD                                Türkçe
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MRI and MRA protocol for Vascular Anomalies 

Vascular Anomalies: Infantile Hemangioma, Congenital Hemangioma, Intramuscular Hemangioma, Non-Involuting Hemangioma, Venous Malformation, Lymphatic Malformation, Lymphatic Venous Malformation, Arteriovenous Malformation (AVM), Arteriovenous  Fistula (AVF), Klippel-Trenanunay Syndrome, Parks Weber Syndrome, Proteus  Syndrome , Maffucci Syndrome

Abbreviations: FSE: Fast Spin-echo, PD: Proton Density, GE: Gradient-echo, FS: Fat Suppression, SO: Slice Orientation, ST: Slice Thickness (mm), IT: Imaging Time

 

 

SO

 TR/TE FS ST IT Why
1 Axial; Coronal and/or sagittal (+/-)  T1 SE - 3-5 - Soft tissues (muscles, bones etc.) are assessed; to assess if there is fat within the lesion, any hemorrhage or blood products in or around the lesion or any flow voids that may be related to high flow anomalies (e.g., AVM, fistula). Also, phleboliths can be searched within the diseased area (if phleboliths are seen, it would be very suggestive of a venous malformation). 
2 Axial: Coronal and/or sagittal (+/-)  T2-FSE veya STIR + 3-5 - The extent of the lesion (particularly low flow anomalies such as venous and lymphatic malformations) and relationship of the lesion with other soft tissue structures can be best appreciated using this sequence. If the lesion is a high flow anomaly (AVM, AVF), flow voids are seen. 
3 Axial, Coronal or sagittal GE, 3800/85, FA:-

No saturation "slab"

- 3-5 - Primarily used to determine if the lesion is high- or low-flow anomaly. If high signals are seen, the lesion is considered to be a high flow anomaly (AVM, AVF).
4 Axial, Coronal or sagittal Post-Contrast- MRA, 3000/120 - 3-5 - In general, this is used in addition to MRI (If not desired, this can be skipped). It is particularly helpful to assess the vascular architecture including arteries and veins of the malformation. It may be quite useful if embolization is a potential treatment method for the lesion (AVM, fistula). 
5 Axial, Coronal or sagittal Post-Contrast T1 SE + - - This sequence is particularly useful to distinguish venous malformations from lymphatic malformations. If the lesion shows contrast enhancement it is considered to be "venous", if not, it is considered a lymphatic lesion.  

Axial T1-SE MR images: 1st image shows a venous malformation in the toe; the lesion can not be separated easily from other soft tissues. 2nd image is an AVM lesion (knee). There are multiple small hipointensities representing flow voids related to fast flow vessels of the malformation.  

     

Axial T2-FSE MR images (with fat suppression): 1st image shows a venous malformation in the elbow. The borders of the lesion can easily be determined using this sequence. 2nd image shows an AVM in the knee, demonstrating multiple various size signal voids in the muscles, as well as within the bone. 

       

Axial GE MR images

1st image is a lymphatic malformation; demonstrating no signals within the lesion. The bright signals are related to normal extremity vessels. 2nd image shows an AVM, demonstrating high signals due to high flow vessels.  

    

Post-Contrast MRA (Magnetic Resonance Angiography) imagesAll images (below) are demonstrating high flow anomalies. 1st image is an AVM in the leg, 2nd image is a lesion considered to be intramuscular hemangioma demonstrating multiple arterial feeders of the lesion. 3rd image demonstrates a congenital arteriovenous fistula (AVF) in the calf.  

           

Post-contrast T1 SE (with fat suppression) MR imagesİ

1st image is an axial post-contrast T1 image of the knee. There is significant contrast enhancement seen within the lesion (Venous Malformation). Lymphatic malformations do not show contrast enhancement or show very minimal peripheral contrast enhancement. 2nd image shows multiple venous malformations in the liver (Blue Rubber Bleb Nevus Syndrome).  

    

 

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Disclaimer: This page is intended to be an alternative source for medical professionals who deal with magnetic resonance, in clinical practice or research, but should not replace a formal education, teaching or training in the field. The author of this web source, Orhan Konez, MD, claims no responsibility for the accuracy of this information, data or images. This web page does not establish any form of consultation with Dr. Konez.  Information, statements or images can not be copied, duplicated and distributed in any form without permission.     

 

Links:

http://www.konez.com/ufe.htm  -  Fibroid embolization 

http://www.konez.com/laser.htm - Laser ablation of varicose veins

http://www.konez.com/centralcatheters.htm - Central Catheters